depurativo

(en territorios con usos significativos TRAMIL)

Jamaica:

  • rice bitters
Usos tradicionales significativos TRAMIL

partes aéreas o planta entera, fresca o seca, decocción, vía oral1

*depurativo: tomado como medida profiláctica para mantener la salud mejorando la desintoxicación y ayudando a reducir la acumulación de productos metabólicos de desecho en el cuerpo. Algunos encuestados afirman que la "limpieza" de la sangre resuelve cualquier problema de piel1.

Recomendaciones Preparación y Dosificación Referencias

De acuerdo con la información disponible:

El uso de las partes aéreas o la planta entera en decocción por vía oral como depurativo, se clasifica como REC con base en el empleo significativo tradicional documentado en las encuestas TRAMIL, los estudios de toxicidad y la información científica publicada.

No usar durante el embarazo, la lactancia2,3 ni en niños menores de 12 años.

Para el “blood cleanse” (depurativo):
preparar una decocción con 3 gramos de las partes aéreas o de la planta entera en 1 taza de agua (250 mililitros), hervir 10 minutos en recipiente tapado. Dejar enfriar, colar (filtrar) y beber 2 tazas al día.

Ninguna preparación debe guardarse por más de 24 horas, ni fuera de refrigeración.

1 PICKING D, MITCHELL S, DELGODA R, YOUNGER N, 2011
TRAMIL survey. Natural Products Institute, The Biotechnology Centre & Tropical Metabolic Research Institute, University of the West Indies, Mona, Jamaica.

2 BONE K, 1999
Clinical applications of Ayurvedic and Chinese Herbs. Queensland, Australia: Phytotherapy Press.

3 WHO, 2004
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4 SHARMA A, KRISHAN L, HANDA SS, 1992
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5 WEIMING C, XIAOTIAN L, 1982
Deoxyandrographolide-19beta-D-glucoside from the leaves of Andrographis paniculata. Planta Med 45:245-246.

6 CHEM W, LIANG X, 1982
Deoxyandrographolide 19ß-D-glucoside from the leaves of A. paniculata. Planta Medica 15:245-246.

7 SIRIPONG P, KONGKATHIP B, PREECHANUKOOL K, PICHA P, TUNSUWAN K, TAYLOR WC, 1992
Cytotoxic diterpenoid constituents from Andrographis paniculata, Nees leaves, J Sci Soc Th 18:187-194.

8 KEEFE JH, GHEEWALA NM, O'KEEFE JO, 2008
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10 CHANG HM, BUT PPH, 1986
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11 MATSUDA T, KUROYANAGI M, SUGIYAMA S, 1994
Cell differentiation-inducing diterpenes from Andrographis paniculata Nees. Chem Pharm Bull (Tokyo) 42:1216-1225.

12 KOTESWARA RAO Y, VIMALAMMA G, RAO CV, TZENG YM, 2004
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13 RAO YK, VIMALAMMA G, RAO CV, TZENG Y, 2004
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14 RAO YK, VIMALAMMA G, RAO CV, TZENG Y, 2010
A new diterpene from the leaves of Andrographis paniculata Nees. Fitoterapia 81(6):610-613.

15 ZAIDAN MRS, NOOR RA, BADRUL AR, ADLIN A, NORAZAH A, ZAKIAH I, 2005
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16 GEORGE M, PANDALAI KM, 1949
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17 NAKANISHI K, SASAKI S, KIANG AK, GOH J, KAKISAWA H, OHASHI M, GOTO M, WATANABE J, YOKOTANI H, MATSUMURA C, TOGASHI M, 1965
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18 LEELARASAMEE A, TRAKULSOMBOON S, SITTISOMWONG N, 1990
Undetectable antibacterial activity of Andrographis paniculata (Burm) Wall. ex Nees. J of the Medical Association of Thailand 73(6):299–304.

19 CHATURVEDI GN, 1983
Clinical studies on kalmegh (Andrographis paniculata) in infectious hepatitis. J of the International Institute of Ayurveda 2:208–211.

20 PURI A, SAXENA R, SAXENA RP, SAXENA KC, SRIVASTAVA V, TANDON JS, 1993
Immunostimulant agents from Andrographis paniculata. J Nat Prod, 56(7):995–999.

21 JARUKAMJORN K, DON-IN K, MAKEJARUSKUL C, LAHA T, DAODEE S, PEARAKSA P, SRIPANIDKULCHAI BO, 2006
Impact of Andrographis paniculata crude extract on mouse hepatic cytochrome P450 enzymes. J Ethnopharmacol 105(3):464-467.

22 CHOUDHURY BR, PODDAR MK, 1984
Andrographolide and kalmegh (Andrographis paniculata) extract: in vivo and in vitro effect on hepatic lipid peroxidation. Methods Find Exp Clin Pharmacol 6(9):481-485.

23 MELCHIOR J, PALM S, WIKMAN G, 1996
Controlled clinical study of standardized Andrographis paniculata extract in common cold. Phytomedicine 3(4):315-318.

24 GABRIELIAN ES, SHUKARIAN AK, GOUKASOVA GI, CHANDANIAN GL, PANOSSIAN AG, WIKMAN G, WAGNER H, 2002
A double blind, placebo-controlled study of Andrographis paniculata fixed combination Kan Jang in the treatment of acute upper respiratory tract infections including sinusitis. Phytomedicine 9(7): 589–597.

25 CHANDER R, SRIVASTAVA V, TANDON JS, KAPOOR NK, 1995
Antihepatotoxic activity of diterpenes of Andrographis paniculata (kalmegh) against Plasmodium berghei-induced hepatic damage in Mastomys natalensis. Pharm Biol 33:135-138.

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Acute and subchronic toxicity studies of Andrographis paniculata in rats and mice. Abstr. the 8th Symp, Faculty of Pharmacy, Chulalongkorn University Bangkok, Thailand.

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Antipyretic activity of six indigenous medicinal plants of Tirumala Hills, Andhra Pradesh, India. J Ethnopharmacol 33:193-196.

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Acute and chronic toxicity of Andrographis paniculata Nee. Th J Pharm Sci 14(2):109-117.

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Testicular toxicity assesment of Andrographis paniculata dried extract in rats. J Ethnopharmacol 58:219-224.

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